<h1 class="ql-align-center">Fragile X Syndrome</h1> <h2>About:</h2> <ul><li>Fragile X syndrome(FXS)&nbsp;is also known as&nbsp;Martin-Bell syndrome or Marker X syndrome.</li></ul> <ul><li>Fragile X syndrome is a genetic condition that causes a range of developmental problems including learning disabilities and cognitive impairment</li></ul> <ul><li>The syndrome is the leading inherited cause of&nbsp;autism in 4% of the population worldwide.&nbsp;</li></ul> <ul><li>Usually, males are more severely affected by this disorder than females.</li></ul> <ul><li>This is caused by changes in a gene called FMR1 which makes an important protein (FMRP). This protein is required for brain development.</li></ul> <ul><li>Spread of the disease: </li></ul> <ul><li class="ql-indent-1">A mother who is a carrier has a 50% chance of passing the mutated gene to her children, who will either be carriers or have FXS.</li></ul> <ul><li class="ql-indent-1">Men who are carriers do not pass the pre-mutation to their sons, but only daughters, who become carriers</li></ul>